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Brk Polyclonal Antibody, 50ul[BT-AP00976] Serological Pipets It functions as a receptor

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Brk Polyclonal Antibody, 50ul[BT-AP00976] Serological Pipets It functions as a receptorThe protein encoded by PTK6 (protein tyrosine kinase 6) is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of PTK6 in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of PTK6 has been detected at low levels in some breast tumors but not in normal breast tissue. The

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Description

It functions as a receptor for endogenous ligands

beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery

and may also have a role in controlling cell growth and/or differentiation

Alternatively spliced transcript variants encoding different isoforms have been found for HRH2

Mutations in this gene cause Alexander disease

Brk Polyclonal Antibody, 50ul[BT-AP00976] Serological Pipets It functions as a receptorThe protein encoded by PTK6 (protein tyrosine kinase 6) is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of PTK6 in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of PTK6 has been detected at low levels in some breast tumors but not in normal breast tissue. The

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