p27 Polyclonal Antibody, 50ul[BT-AP06755] Human Genome Knockout Libraries Mutations in this gene result

Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia

It is a multifunctional protein found in plasma

Two transcript variants that encode different isoforms have been found for ZAP70

Disrupts the interaction between DNA and TCF4

and other foreign compounds

p27 Polyclonal Antibody, 50ul[BT-AP06755] Human Genome Knockout Libraries Mutations in this gene resultCDKN1B encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The cyclin dependent kinase inhibitor 1B binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the