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In a rat wound model and in rat dermal fibroblast cultures, GHK-Cu increased type I collagen and glycosaminoglycan production and modulated the expression of the dermal proteoglycans decorin and biglycan

It works at the level of the mitochondria to improve: Insulin sensitivity Metabolic flexibility Glucose regulation Exercise adaptation Improving resting metabolic rate and ensuring enough sleep can further enhance the metabolic benefits of MOTS-c

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This process results in both reduced serotonin production as well as increased production of quinolinic acid, which functions as an agonist of the NMDA glutamate receptor (53)

Machida, S., & Booth, F

Nutritional and herbal interventions for polycystic ovary syndrome (PCOS): a comprehensive review of dietary approaches, macronutrient impact, and herbal medicine in management