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Reviews and meta-analyses report variable lean mass outcomes during GLP-1RA therapy

The dosage provided to Mo Farah was well within the 50ml limit permitted

The active ingredient concentration ranges from 2.4 mg/3 mL to 5 mg/mL depending on formulation, with inactive components selected to maintain peptide stability and sterility in licensed 503A pharmacy settings

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However, more serious reactions have been reported, like pancreatitis, kidney problems, and an increased risk of diabetic retinopathy complications in those with a history of diabetic eye disease

To date, Phase 3 clinical trial data have also shown significant weight-loss outcomes, including up to 28.7% average body weight loss at 68 weeks in one obesity trial and 16.8% average weight loss at 40 weeks in adults with type 2 diabetes, with additional Phase 3 readouts still expected throughout 2026