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Lysophosphatidate signaling stabilizes Nrf2 and increases the expression of genes involved in drug resistance and oxidative stress responses: implications for cancer treatment

Nat Rev Clin Oncol 14:100113

The gentle approach is to use fat like an accent, not the whole meal

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It is rapidly moving away from viral hepatitis as the sole primary driver of chronic liver morbidity and mortality, and overwhelmingly towards conditions rooted in metabolic dysfunction (Huang et al., 2025)