AEE788 igomycin A Wardlaw AJ

Wardlaw AJ

Topical CFTR Inhibitor II (10 μM) in mice rapidly and reversibly inhibits forskolin-induced hyperpolarization in nasal potential differences

Pirfenidone

Formula: C34H50N4O9S

demonstrating potent antagonist activity

AEE788 igomycin A Wardlaw AJAEE 788 is an orally bioavailable multiple receptor tyrosine kinase inhibitor. AEE788 inhibits phosphorylation of the tyrosine kinases of epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2), and vascular endothelial growth factor receptor 2 (VEGF2), resulting in receptor inhibition, the inhibition of cellular proliferation, and induction of tumor cell and tumor associated endothelial cell apoptosis. Check for