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Nat Rev Rheumatol 13:155163 Verlaan L, Boekesteijn RJ, Oomen PW, Liu WY, Peters M, Witlox MA et al (2018) Biomechanical alterations during sit-to-stand transfer are caused by a synergy between knee osteoarthritis and obesity

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MOTS-c is a naturally occurring protein hormone and experimental therapeutic peptide composed of 16 amino acids

Another study involved 64 patients with impaired glucose metabolism and biopsy-proven NAFLD who were randomly assigned to receive metformin or rosiglitazone or metformin plus rosiglitazone for 12 months

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