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This is particularly noteworthy because two competing oral small-molecule GLP-1 programs from Pfizer, lotiglipron (discontinued in 2023) and danuglipron (discontinued in April 2025), were terminated due to liver toxicity concerns

As expected, the KD of Bhlhe40 in epidermal cells significantly impaired their ability to induce hair regeneration from the skin organoids posttransplantation (Fig

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Altogether, this highlights the importance of gaining more insights in the role of non-Helicobacter pylori Helicobacter species in neurological diseases

As we expected, either GLP-1R blockade or PKA inhibition partially eliminated the protective effects of the combined therapy on endothelial function

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