WS3 - β Cell Proliferation Inducer. CAS# 1421227-52-2 Catalog No.:M60095-2S ATM-dependent hyper-radiosensitivity in mammalian cells

ATM-dependent hyper-radiosensitivity in mammalian cells irradiated by heavy ions

Overcoming Bcr-Abl T315I mutation by combination of GNF-2 and ATP competitors in an Abl-independent mechanism

Epub 2015 Apr 1

Discovery of potent and selective covalent inhibitors of JNK

Lawnicka H

WS3 - β Cell Proliferation Inducer. CAS# 1421227-52-2 Catalog No.:M60095-2S ATM-dependent hyper-radiosensitivity in mammalian cellsWS3, CAS No. 1421227 52 2, is a highly potent and selective small molecule that promotes pancreatic cell and RPE cells expansion, identified by a high throughput, cell based screening. It can induce proliferation of mouse R7T1 cells with an EC50 ~0. 074 M, and expansion of primary rat and human cells in dissociated and intact islet format with similar EC50. WS3 can also reversibly proliferate primary RPE cells isolated from fetal and adult human