Go6893 - PKC Inhibitor. CAS# 133053-19-7 60432 10(9):837-46

10(9):837-46

It was shown to reduce S-phase cells and induce G1-phase cells in A2780 cells

1-dioxidotetrahydro-2H-thiopyran-4-yl)-5-ethyl-4-oxo-7-(3-(trifluoromethyl)phenyl)-4

evidenced by caspase and poly (ADP-ribose) polymerase cleavage

32)33)34-18-26-29-30-27(35-23-7-3-4-8-23)31(26)21-6-5-15-28-17-21/h5-6

Go6893 - PKC Inhibitor. CAS# 133053-19-7 60432 10(9):837-46Go6983, CAS No. 133053 19 7, is a potent pan PKC inhibitor against for PKC, PKC, PKC, PKC and PKC with IC50 of 7 nM, 7 nM, 6 nM, 10 nM and 60 nM, respectively. It is inactive to PKC. Go6983 displays cardioprotective properties. It can reduce polymorphonuclear leukocyte adherence and infiltration following myocardial ischemia reperfusion injury. It can also optimize nave human pluripotent stem cell growth and viability following nave cell derivation