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Pomalidomide 4-PEG1-amine - CAS# 2154342-56-8 050 doi: 1158/1535-7163

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Pomalidomide 4-PEG1-amine - CAS# 2154342-56-8 050 doi: 1158/1535-7163Pomalidomide 4 PEG1 amine, CAS No. 2154342 56 8, cereblon ligand with PEG linker and terminal amine for onward chemistry. Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG1 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. Product information CAS Number: 2154342 56 8 Molecular Weight: 396. 83

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Description

doi: 1158/1535-7163

ABT-199 is a much improved lead compound over the original ABT-263 (navitoclax) to avoid thrombocytopenia caused by BCL-XL inhibition

G6 treated Conduritol B epoxide-N2a also has significantly decreased GS

The first class (DuP-753 sensitive) represents approximately 85% of the total binding sites for AII and possesses a high affinity (IC50 of 92

48(3):317-23

Pomalidomide 4-PEG1-amine - CAS# 2154342-56-8 050 doi: 1158/1535-7163Pomalidomide 4 PEG1 amine, CAS No. 2154342 56 8, cereblon ligand with PEG linker and terminal amine for onward chemistry. Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG1 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. Product information CAS Number: 2154342 56 8 Molecular Weight: 396. 83

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