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BMS-813160 - CAS# 1286279-29-5 205 The absolute oral bioavailability is

BMS-813160 - CAS# 1286279-29-5 205 The absolute oral bioavailability is

Name: BMS-813160 - CAS# 1286279-29-5 205 The absolute oral bioavailability is
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BMS-813160 - CAS# 1286279-29-5 205 The absolute oral bioavailability isBMS 813160, CAS No. 1286279 29 5, is a potent and selective CCR2 CCR5 antagonist with potential immunomodulating and antineoplastic activities. BMS 813160 specifically binds and prevents the activation of both CCR2 and CCR5. This inhibits the activation of CCR2 CCR5 mediated signal transduction pathways and may inhibit inflammatory processes, angiogenesis, tumor cell migration, tumor cell proliferation and invasion. Product information CAS Number:

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Description

The absolute oral bioavailability is modest in mouse

Smiles: [O-][N+](=O)C1=CC(=C(Cl)C=C1)C(=O)NC1C=CC=CC=1

5-e]azepin-4-yl)acetamide

73(11):3336-3346

PubMed PMID: 25381820

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