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By protecting the mitochondria, glutathione may also help to manage inflammation and ward against more serious autoimmune conditions

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The presence of high serum bicarbonate could indicate chronic respiratory acidosis [typical of chronic obstructive pulmonary disease (COPD)] or metabolic alkalosis (secondary to vomiting, use of thiazide diuretics, or excess mineralocorticoids) (336)

Decreased levels of proapoptotic factors and increased key regulators of mitochondrial biogenesis constitute new potential beneficial features of long-lived growth hormone receptor gene-disrupted mice