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AML patients with IDH1 or IDH2 mutations treated with hypomethylating agents: A case series

doi:10.1016/j.pscychresns.2021.111302 114. Sohal, V

The underlined mechanism involves CGA-mediated excessive ROS production, causing mitochondrial dysfunction, leading to increases in cleaved levels of caspase-3, caspase-9, PARP, and Bax/Bcl-2 ratio [297,298]