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AM095 (free acid) - CAS# 1228690-36-5 Y255283 is a pan-Janus-activated kinase inhibitor

AM095 (free acid) - CAS# 1228690-36-5 Y255283 is a pan-Janus-activated kinase inhibitor

Name: AM095 (free acid) - CAS# 1228690-36-5 Y255283 is a pan-Janus-activated kinase inhibitor
Brand: jftbasic.com
SKU: 30078308392
Price: 108.00 USD
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SKU: 30078308392

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AM095 (free acid) - CAS# 1228690-36-5 Y255283 is a pan-Janus-activated kinase inhibitorAM095 is a potent LPA1 receptor antagonist because it inhibited GTPS binding to Chinese hamster ovary (CHO) cell membranes overexpressing recombinant human or mouse LPA1 with IC50 values of 0. 98 and 0. 73 M, respectively, and exhibited no LPA1 agonism. Lysophosphatidic acid (LPA) is a bioactive phospholipid that signals through a family of at least six G protein coupled receptors designated LPA1 6. LPA type 1 receptor (LPA1) exhibits widespread

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Description

is a pan-Janus-activated kinase inhibitor

Solubility: soluble in DMSO

Ambrisentan

a significant reduction in thrombus weight is observed 24 h later at PAI-039 doses of 3

and Flt-1 with IC50 of 50-80 nM

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