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Other sites of extrahepatic drug metabolism include epithelial cells of the GI tract, lungs, kidneys, and skin

The most dramatic weight loss usually happens between months 3-8 as doses escalate

In addition, some studies on recently marketed GLP-1 RAs such as dulaglutide (AWARD studies), albiglutide (HARMONY studies), and lixisenatide (GetGoal studies) included cardiovascular parameters as a part of their non-primary endpoints (Table 2)