Epalrestat - CAS# 82159-09-9 752 Chemical Name: N-[4-({[4-(4-methoxyphenyl)oxan-4-yl]methyl}carbamoyl)phenyl]furan-2-carboxamide

Chemical Name: N-[4-({[4-(4-methoxyphenyl)oxan-4-yl]methyl}carbamoyl)phenyl]furan-2-carboxamide

InChi: InChI=1S/C30H42N2O9/c1-5-22-23(19-28(35)32(11-13-37-2)12-14-38-3)29(25(34)20-24(22)33)30(36)21-6-7-26(27(18-21)39-4)41-17-10-31-8-15-40-16-9-31/h6-7

Formula: C23H27ClN2O2

As a prodrug

Smiles: COC1=CC2CC[C@H]3[C@@H]4CC[C@H](NCCCCCCN5C(=O)C=CC5=O)[C@@]4(C)CC[C@@H]3C=2C=C1

Epalrestat - CAS# 82159-09-9 752 Chemical Name: N-[4-({[4-(4-methoxyphenyl)oxan-4-yl]methyl}carbamoyl)phenyl]furan-2-carboxamideEpalrestat is an aldose reductase inhibitor that is currently available for the treatment of diabetic neuropathy. In vivo, Epalrestat treatment significantly ameliorated the bleomycin mediated histological fibrosis alterations and blocked collagen deposition concomitantly with reversing bleomycin induced expression up regulation of TGF 1, AR, SMA and collagen I (both mRNA and protein). Product information CAS Number: 82159 09 9 Molecular Weight: 319.