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Such risks and uncertainties include, without limitation: the early-stage nature of the Companys product development activities, including the transdermal delivery platform currently under development, and the inherent uncertainties associated therewith

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The human results are mixed, with small open-label studies encouraging but the controlled phase 2 OVERTURE trial missing its primary endpoint, and the larger pivotal trial has finished enrolling with results pending, so for now it is best read as mechanistically promising and clinically unproven