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The beneficial effects of GLP-1RAs on septic lung injury were similarly confirmed by Guo et al (60), who found that liraglutide treatment in mice with sepsis induced by bacterial pneumonia could reduce the bacterial load, improve animal survival rates, decrease lung inflammatory cells and cytokines, and enhance the production of pulmonary surfactant phospholipids and surfactant proteins A and B, thereby alleviating acute lung injury and mortality due to pneumonia-induced sepsis

The treated cells also exhibited an extended replicative lifespan surviving 10 additional passages beyond the Hayflick limit observed in controls without evidence of malignant transformation

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Efect of upper gastrointestinal disease on the pharmacokinetics of oral semaglutide in subjects with type 2 diabetes

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