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Among metabolic detoxification enzymes, GST is a family of multifunctional enzymes that are ubiquitously present in eukaryotes and prokaryotes, playing an important role in the detoxification of numerous endogenous and exogenous compounds

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While these genes are likely involved in the development of excessive eating and obesity in individuals with PWS, none of them fully explain the entire PWS phenotype

Additionally, ongoing research suggests potential applications of Melanotan 2 in weight loss through appetite suppression and sexual desire disorders due to its interactions with melanocortin receptors