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HLA-DOBeta Polyclonal Antibody, 100ul Modification Enzymes EFTUD2 encodes a GTPase which

SKU: 99907271116

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HLA-DOBeta Polyclonal Antibody, 100ul Modification Enzymes EFTUD2 encodes a GTPase whichHLA DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26 28

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Description

EFTUD2 encodes a GTPase which is a component of the spliceosome complex which processes precursor mRNAs to produce mature mRNAs

is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II

It relocalizes to the plasma membrane under conditions of elevated extracellular copper

The encoded preproprotein is proteolytically processed to generate the mature procollagen N-proteinase

It interacts with dyskerin

HLA-DOBeta Polyclonal Antibody, 100ul Modification Enzymes EFTUD2 encodes a GTPase whichHLA DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26 28

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