LMX1B Polyclonal Antibody, 50ul Shakers Two encoded proteins

Two encoded proteins

Potential regulator of neural basic helix-loop-helix genes

dermis and tendon

Mutations have also been associated with non-insulin-dependent diabetes mellitus type II| an autosomal dominant disease of defective insulin secretion

PTTG1IP (pituitary tumor-transforming 1 interacting protein) encodes a single-pass type I integral membrane protein

LMX1B Polyclonal Antibody, 50ul Shakers Two encoded proteinsLMX1B encodes a member of LIM homeodomain family of proteins containing two N terminal zinc binding LIM domains, 1 homeodomain, and a C terminal glutamine rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail patella syndrome.