DOC11 Polyclonal Antibody, 100ul Cell Culture Members of this family are

Members of this family are characterized by long N-termini and multiple functional domains

This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2| and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1| MAP3K2/MEKK2|MAP3K3/MEKK5| and MAP4K2/GCK

The protein lacks the cytoplasmic domain characteristic of other cadherins

The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity

which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes

DOC11 Polyclonal Antibody, 100ul Cell Culture Members of this family areThe DHR 2 domain is necessary for the GEF activity.,Guanine nucleotide exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP.,miscellaneous:'Zizim' means 'spike' in Hebrew.,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the DOCK family.,Contains 1 DHR 1 (CZH 1) domain.,Contains 1 DHR 2 (CZH 2) domain.,Contains 1 PH domain.,subunit: Interacts with CDC42.,