KLHL3 Polyclonal Antibody, 50ul Subcellular Fractions It associates with the signaling

It associates with the signaling lymphocyte-activation molecule

transcription and other nuclear processes by acetylating histone and nonhistone proteins

and thus regulate the activity of

The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP

which encode a phylogenetically conserved family of transcription factors that regulate a variety of developmental processes

KLHL3 Polyclonal Antibody, 50ul Subcellular Fractions It associates with the signalingKLHL3 is ubiquitously expressed and encodes kelch like family member 3 which has an N terminal BTB domain followed by a BACK domain and six kelch like repeats in the C terminus. These kelch like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D); a rare