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GSK3 beta(Phospho Ser9) Polyclonal Antibody, 20ul Fluorescent Staining 53BP1 activates the checkpoint kinase

SKU: 99450640617

4.3
USD97.20 USD147.20

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GSK3 beta(Phospho Ser9) Polyclonal Antibody, 20ul Fluorescent Staining 53BP1 activates the checkpoint kinaseThe protein encoded by this gene is a serine threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants

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Description

53BP1 activates the checkpoint kinase ATM and promotes DNA double strand break repair via nonhomologous end joining (NHEJ) repair pathway

is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II

The protein encoded by this gene is part of a large multisubunit complex required for microtubule nucleation at the centrosome

May act downstream of P38-kinase and BCL-2

Coexpression of this protein with CDC42 suggested a role of this protein in actin filament assembly and cell shape control

GSK3 beta(Phospho Ser9) Polyclonal Antibody, 20ul Fluorescent Staining 53BP1 activates the checkpoint kinaseThe protein encoded by this gene is a serine threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants

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