HIF-1 alpha (Acetyl Lys532) Rabbit Polyclonal Antibody, 20ul Cell Dissociation Mutations in this gene result

Mutations in this gene result in pseudohypoaldosteronism type IIB

a transcriptional activator that is required for B-lymphocyte transformation

characterized by the lack of the A subunit alone

The different transcripts result from the use of alternate transcription initiation sites

part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human

HIF-1 alpha (Acetyl Lys532) Rabbit Polyclonal Antibody, 20ul Cell Dissociation Mutations in this gene resultContains two independent C terminal transactivation domains NTAD and CTAD which function synergistically. Their transcriptional activity is repressed by an intervening inhibitory domain (ID). Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions activates the transcription of over 40 genes including erythropoietin glucose transporters glycolytic enzymes vascular endothelial growth factor and