Collagen IV alpha2 (Cleaved-Ser1485) Rabbit Polyclonal Antibody, 50ul Culture Plate Inserts -delta and -epsilon

-delta and -epsilon

Members of this family function as GEPs for ADP-ribosylation factors (ARFs)| which are guanine nucleotide-binding proteins involved in vesicular trafficking pathways

leads to the genetic disorder α1-antitrypsin deficiency

the Salvador-Warts-Hippo (SWH) pathway

A frequent polymorphism in the translation start codon of this gene can abolish translation and may be associated with forms of deafness

Collagen IV alpha2 (Cleaved-Ser1485) Rabbit Polyclonal Antibody, 50ul Culture Plate Inserts -delta and -epsilonAlpha chains of type IV collagen have a non collagenous domain (NC1) at their C terminus frequent interruptions of the G X Y repeats in the long central triple helical domain (which may cause flexibility in the triple helix) and a short N terminal triple helical 7S domain. Type IV collagen is the major structural component of glomerular basement membranes (GBM) forming a 'chicken wire' meshwork together with laminins proteoglycans and entactin