ABT1 Rabbit Polyclonal Antibody, 20ul Cell Labeling & Imaging Defects in this gene do

Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged

Epigenetic silencing of this gene has been observed in gliomas

This gene is specifically expressed in the testis

It is also highly expressed in FA B-cells of complementation group A

This protein forms a trimeric complex with cyclin H and MAT2

ABT1 Rabbit Polyclonal Antibody, 20ul Cell Labeling & Imaging Defects in this gene doBasal transcription of genes by RNA polymerase II requires the interaction of TATA binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA.