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Vav(Phospho Tyr160) Polyclonal Antibody, 20ul Site-directed Mutagenesis ras subfamily proteins

SKU: 9719485573

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EUR111.00 EUR148.00

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Vav(Phospho Tyr160) Polyclonal Antibody, 20ul Site-directed Mutagenesis ras subfamily proteinsThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.

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Description

ras subfamily proteins

May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT

The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity

Upon growth factor induction of quiescent cells

This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation

Vav(Phospho Tyr160) Polyclonal Antibody, 20ul Site-directed Mutagenesis ras subfamily proteinsThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.

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