p27(Phospho Thr198) Polyclonal Antibody, 100ul Culture Tubes PENK(proenkephalin) encodes a preproprotein that

PENK(proenkephalin) encodes a preproprotein that is proteolytically processed to generate multiple protein products

one protein-coding and one not

This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19

The protein encoded by this gene contains a zinc finger at the N-terminus| and is thought to bind to a histone modification site that regulates gene expression

Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends

p27(Phospho Thr198) Polyclonal Antibody, 100ul Culture Tubes PENK(proenkephalin) encodes a preproprotein thatThis gene encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The encoded protein binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from