Sgo1(Phospho Ser14) Polyclonal Antibody, 20ul Lentiviral Packaging reducing fatigue and offering a

reducing fatigue and offering a smoother

This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization

and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms

in contrast to the other GAP1 family members

Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis

Sgo1(Phospho Ser14) Polyclonal Antibody, 20ul Lentiviral Packaging reducing fatigue and offering aThe protein encoded by this gene is a member of the shugoshin family of proteins. This protein is thought to protect centromeric cohesin from cleavage during mitotic prophase by preventing phosphorylation of a cohesin subunit. Reduced expression of this gene leads to the premature loss of centromeric cohesion, mis segregation of sister chromatids, and mitotic arrest. Evidence suggests that this protein also protects a small subset of cohesin found