SNAI2 Rabbit Polyclonal Antibody, 100ul Gene Editing Overexpression of PTK6 in mammary

Overexpression of PTK6 in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype

The protein functions as a regulator of RNA polymerase II-mediated transcription through elongation and chromatin remodeling functions

Cell division cycle 16 encoded by CDC16 functions as a protein ubiquitin ligase and is a component of the multiprotein APC complex

The protein encoded by IL2RB represents the beta subunit and is a type I membrane protein

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SNAI2 Rabbit Polyclonal Antibody, 100ul Gene Editing Overexpression of PTK6 in mammaryThis gene encodes a member of the Snail family of C2H2 type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E box motifs and is also likely to repress E cadherin transcription in breast carcinoma. This protein is involved in epithelial mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.