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PYK2 Polyclonal Antibody, 20ul[BT-AP07522] Polyclonal Antibody Preparation Mutations in this gene have

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PYK2 Polyclonal Antibody, 20ul[BT-AP07522] Polyclonal Antibody Preparation Mutations in this gene havePTK2B encodes a cytoplasmic protein tyrosine kinase which is involved in calcium induced regulation of ion channels and activation of the map kinase signaling pathway. protein tyrosine kinase 2 beta may represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. protein tyrosine kinase 2 beta undergoes rapid tyrosine

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Description

Mutations in this gene have been associated with Specific Granule Deficiency

As a modulator of the nodal signaling cascade

The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin

The protein encoded by TFAP2C is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes

Tissue-specific utilization of alternative polyA-signal has been described in literature

PYK2 Polyclonal Antibody, 20ul[BT-AP07522] Polyclonal Antibody Preparation Mutations in this gene havePTK2B encodes a cytoplasmic protein tyrosine kinase which is involved in calcium induced regulation of ion channels and activation of the map kinase signaling pathway. protein tyrosine kinase 2 beta may represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. protein tyrosine kinase 2 beta undergoes rapid tyrosine

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