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4E-BP1 Polyclonal Antibody, 100ul[BT-AP00035] Immune Repertoire Sequencing This receptor is preferentially expressed

SKU: 95045638426

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4E-BP1 Polyclonal Antibody, 100ul[BT-AP00035] Immune Repertoire Sequencing This receptor is preferentially expressedEIF4EBP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV

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Description

This receptor is preferentially expressed in mature B lymphocytes

but this repression is then overcome by differentiation signals

Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene

It is thought that this protein may be involved in oocyte maturation and follicular development as a homodimer or by forming heterodimers with a related protein

SLC7A10| in association with 4F2HC (SLC3A2

4E-BP1 Polyclonal Antibody, 100ul[BT-AP00035] Immune Repertoire Sequencing This receptor is preferentially expressedEIF4EBP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV

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