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CD264 Polyclonal Antibody, 100ul Liquid Storage Consumables The encoded type 2 transmembrane

SKU: 94658494271

4.1
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CD264 Polyclonal Antibody, 100ul Liquid Storage Consumables The encoded type 2 transmembraneThe protein encoded by TNFRSF10D (TNF receptor superfamily member 10d) is a member of the TNF receptor superfamily. This receptor contains an extracellular TRAIL binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL induced cell apoptosis.

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Description

The encoded type 2 transmembrane protein may play a role in inflammatory and immune response

This gene belongs to the non-CT (non cancer/testis) subgroup of the melanoma-associated antigen (MAGE) superfamily

The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest| and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells

POLR3D (RNA polymerase III subunit D) complements a temperature-sensitive mutant isolated from the BHK-21 Syrian hamster cell line

Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor

CD264 Polyclonal Antibody, 100ul Liquid Storage Consumables The encoded type 2 transmembraneThe protein encoded by TNFRSF10D (TNF receptor superfamily member 10d) is a member of the TNF receptor superfamily. This receptor contains an extracellular TRAIL binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL induced cell apoptosis.

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