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CD58 Polyclonal Antibody, 50ul[BT-AP02462] ssDNA Synthesis KLK11 is one of the

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CD58 Polyclonal Antibody, 50ul[BT-AP02462] ssDNA Synthesis KLK11 is one of theKRT14 encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12 p11.

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Description

KLK11 is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19

The V1 domain consists of three A and three B subunits

It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide

An important paralog of this gene is NPY1R

Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle| proliferation| and developmental processes

CD58 Polyclonal Antibody, 50ul[BT-AP02462] ssDNA Synthesis KLK11 is one of theKRT14 encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12 p11.

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