DPY30 Rabbit Polyclonal Antibody, 50ul Cell Screening and Imaging Mutations in ITCH are a

Mutations in ITCH are a cause of syndromic multisystem autoimmune disease

Involved in calcium homeostasis

These exonucleases include the family of DNA polymerases

particularly on chromosomes Y and 15

Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD)

DPY30 Rabbit Polyclonal Antibody, 50ul Cell Screening and Imaging Mutations in ITCH are aThis gene encodes an integral core subunit of the SET1 MLL family of H3K4 methyltransferases. The encoded protein directly controls cell cycle regulators and plays an important role in the proliferation and differentiation of human hematopoietic progenitor cells.