Raf-1 Polyclonal Antibody, 100ul[BT-AP13536] Nucleic Acid Extraction Translocations resulting in fusion proteins

Translocations resulting in fusion proteins with both CRTC1 and CRTC3 have been implicated in the development of mucoepidermoid carcinomas

and thus terminates signal transmission

This gene encodes a member of the NF-kappa-B inhibitor family| which contain multiple ankrin repeat domains

They are very similar and it is therefore difficult to provide a clear and unambiguous protein sequence

Anti-apoptotic protein which functions as a caspase-3 inhibitor

Raf-1 Polyclonal Antibody, 100ul[BT-AP13536] Nucleic Acid Extraction Translocations resulting in fusion proteinsThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.