GLP1R Polyclonal Antibody, 20ul Immuno Plates PTGDR (prostaglandin D2 receptor) encodes

PTGDR (prostaglandin D2 receptor) encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily

The protein may also play a role in the morphological organization of liver and intestine

Mutations in PMS2 have been associated with hereditary nonpolyposis colorectal cancer (HNPCC

Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported

Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms

GLP1R Polyclonal Antibody, 20ul Immuno Plates PTGDR (prostaglandin D2 receptor) encodesThis gene encodes a 7 transmembrane protein that functions as a receptor for glucagon like peptide 1 (GLP 1) hormone, which stimulates glucose induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP 1 and GLP 1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene