SEN15 Rabbit Polyclonal Antibody, 20ul Electronic Pipette Mutations in this gene are

Mutations in this gene are associated with the French-Canadian type of Leigh syndrome

It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions

which has been shown to be essential for development of the heart-like dorsal vessel

6-bisphosphate levels in the liver and muscle

The core complex associates with MTA2| MBD2| MBD3| MTA1L1| CHD3 and CHD4 to form the nucleosome remodeling and histone deacetylation (NuRD) complex| or with SIN3| SAP18 and SAP30 to form the SIN3 HDAC complex

SEN15 Rabbit Polyclonal Antibody, 20ul Electronic Pipette Mutations in this gene areThis gene encodes a subunit of the tRNA splicing endonuclease which catalyzes the removal of introns from tRNA precursors. Alternative splicing results in multiple transcript variants. There is a pseudogene of this gene on chromosome 17.