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CSPG4 Polyclonal Antibody, 50ul Serological Pipets Mutations in this gene result

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CSPG4 Polyclonal Antibody, 50ul Serological Pipets Mutations in this gene resultA human melanoma associated chondroitin sulfate proteoglycan plays a role in stabilizing cell substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.

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Description

Mutations in this gene result in Hartnup disorder

amenorrhea and disordered steroidogenesis

ABCC12 and another subfamily member are arranged head-to-tail on chromosome 16q12

This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response

The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes

CSPG4 Polyclonal Antibody, 50ul Serological Pipets Mutations in this gene resultA human melanoma associated chondroitin sulfate proteoglycan plays a role in stabilizing cell substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.

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