Cardiotrophin-1 Polyclonal Antibody, 20ul[BT-AP01170] Cytokines 250mL*3pcs

250mL*3pcs

The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies

and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction

This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1

and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization

Cardiotrophin-1 Polyclonal Antibody, 20ul[BT-AP01170] Cytokines 250mL*3pcsThe protein (cardiotrophin 1) encoded by CTF1 is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST gp130 receoptor. Two transcript variants encoding different isoforms have been found for CTF1.