PRAK Monoclonal Antibody, 100ul Insect Expression and high concentrations of the

and high concentrations of the gene product are associated with thrombophilia

and drug resistance in mammary carcinoma

erythropoietic protoporphyria and follicular lymphomas

The protein associates with the U3 small nucleolar ribonucleoprotein 60-80S complexes and may be involved in pre-rRNA processing

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PRAK Monoclonal Antibody, 100ul Insect Expression and high concentrations of theThe protein encoded by this gene is a tumor suppressor and member of the serine threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1 ERK, MAPK14 p38 alpha, and MAPK11 p38 beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein