Arylsulfatase A Polyclonal Antibody, 50ul sgRNA Oligos This gene and other MAGEB

This gene and other MAGEB members are clustered on chromosome Xp22-p21

ADAM17 (ADAM metallopeptidase domain 17) encodes a member of the ADAM (a disintegrin and metalloprotease domain) family

and is likely to be important in developmental processes and cell communication

Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities

an area of frequent loss of heterozygosity in cancers

Arylsulfatase A Polyclonal Antibody, 50ul sgRNA Oligos This gene and other MAGEBThe protein encoded by ARSA hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.