GLCNE Polyclonal Antibody, 20ul Polyclonal Antibodies The encoded kinase may activate

The encoded kinase may activate cyclin-dependent kinase 2 and is involved in cell growth

The signalling and trafficking of this receptor are regulated by multiple factors

upon ligand binding

a ubiquitous protein kinase which regulates metabolic pathways

and has been linked to primary microcephaly and Alzheimer's disease

GLCNE Polyclonal Antibody, 20ul Polyclonal Antibodies The encoded kinase may activateThe glucosamine (UDP N acetyl) 2 epimerase N acetylmannosamine kinase encoded by GNE is a bifunctional enzyme that initiates and regulates the biosynthesis of N acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction.