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Phospho-Akt1 (T72) Polyclonal Antibody, 50ul Plasmid Preparation NBL1 product is the founding

SKU: 89388664706

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Phospho-Akt1 (T72) Polyclonal Antibody, 50ul Plasmid Preparation NBL1 product is the foundingThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

NBL1 product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins

The protein encoded by this gene contains a ring finger motif| which is known to be involved in protein-protein interactions

The protein encoded by this intronless gene belongs to the claudin family

Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al

Mutagenesis analysis demonstrates that this endosomal localization is mediated by the FYVE domain

Phospho-Akt1 (T72) Polyclonal Antibody, 50ul Plasmid Preparation NBL1 product is the foundingThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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