APC5 Polyclonal Antibody, 100ul Cell Dissociation Knockout studies in mice suggested

Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure

High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus

These proteins share considerable sequence similarity over the N-terminal portion of the molecule

and a tyrosine kinase (TK) domain within the cytoplasmic domain

Contains 11 LRR (leucine-rich) repeats

APC5 Polyclonal Antibody, 100ul Cell Dissociation Knockout studies in mice suggestedANAPC5 encodes a tetratricopeptide repeat containing component of the anaphase promoting complex cyclosome (APC C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B type cyclins for 26S proteasome mediated degradation through ubiquitination. The encoded protein (anaphase promoting complex subunit 5) is required for the proper ubiquitination function of APC C and for the