p300(Phospho Ser89) Polyclonal Antibody, 20ul Organelle Studies The phosphodiesterase 10A encoded by

The phosphodiesterase 10A encoded by PDE10A belongs to the cyclic nucleotide phosphodiesterase family

The protein encoded by this gene is highly expressed in peripheral blood of patients with atopic dermatitis (AD)| compared to normal individuals

An important paralog of this gene is SCGB2A2

also referred to as autosomal dominant atrophic macular degeneration

It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells

p300(Phospho Ser89) Polyclonal Antibody, 20ul Organelle Studies The phosphodiesterase 10A encoded byThis gene encodes the adenovirus E1A associated cellular p300 transcriptional co activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co activator of HIF1A (hypoxia inducible factor 1