HSP27 Monoclonal Antibody, 50ul sgRNA Oligos Reduced expression of this gene

Reduced expression of this gene leads to the premature loss of centromeric cohesion

Its initiating methionine residue is post-translationally removed

Several alternatively spliced transcript variants encoding different isoforms of this gene have been described

p53 and BRCA1

and interleukin 1-beta converting enzyme

HSP27 Monoclonal Antibody, 50ul sgRNA Oligos Reduced expression of this geneThe protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot Marie Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN).