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Rabbit Bone Morphogenetic Protein 2, BMP2 ELISA Kit, 96T Polyclonal Antibody Preparation function:Specifically phosphorylates 'Tyr-504' on LCK

SKU: 88127956350

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Rabbit Bone Morphogenetic Protein 2, BMP2 ELISA Kit, 96T Polyclonal Antibody Preparation function:Specifically phosphorylates 'Tyr-504' on LCKInduces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3 EIF2A ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.

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Description

function:Specifically phosphorylates 'Tyr-504' on LCK

Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm

Polymorphisms in this gene influence the ability of individuals to metabolize different drugs

and thereby facilitates cell migration and wound healing

Allelic variants of this gene have been associated with obesity

Rabbit Bone Morphogenetic Protein 2, BMP2 ELISA Kit, 96T Polyclonal Antibody Preparation function:Specifically phosphorylates 'Tyr-504' on LCKInduces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3 EIF2A ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.

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